Publications

Key Scientific Articles

  • Virtanen, K.A., Lidell, M.E., Orava, J., Heglind, M., Westergren, R., Niemi, T., Taittonen, M., Laine, J., Savisto, N.-J., Enerbäck, S., et al. (2009). Functional Brown Adipose Tissue in Healthy Adults. The New England Journal of Medicine. 360, 1518–1525.
  • Orava, J., Nuutila, P., Lidell, M.E., Oikonen, V., Noponen, T., Viljanen, T., Scheinin, M., Taittonen, M., Niemi, T., Enerbäck, S., Virtanen, K.A. (2011). Different metabolic responses of human brown adipose tissue to activation by cold and insulin. Cell Metabolism. 14, 272–279.
  • U Din, M., Saari, T., Raiko, J., Kudomi, N., Maurer, S.F., Lahesmaa, M., Fromme, T., Amri, E.- Z., Klingenspor, M., Solin, O., Nuutila, P., Virtanen, K.A. (2018). Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis. Cell Metabolism. 7;28(2):207-216
  • Orava, J., Nuutila, P., Noponen, T., Parkkola, R., Viljanen, T., Enerbäck, S., Rissanen, A., Pietiläinen, K.H., Virtanen, K.A. (2013). Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans. Obesity. 21, 2279–2287.
  • U Din, M., Raiko, J., Saari, T., Kudomi, N., Tolvanen, T., Oikonen, V., Teuho, J., Sipilä, H.T., Savisto, N., Parkkola, R., Nuutila, P., Virtanen, K.A. (2016). Human brown adipose tissue [15O]O2 PET imaging in the presence and absence of cold stimulus. European Journal of Nuclear Medicine and Molecular Imaging. 43, 1878–1886.
  • Raiko, J., Holstila, M., Virtanen, K.A., Orava, J., Saunavaara, V., Niemi, T., Laine, J., Taittonen, M., Borra, R.J.H., Nuutila, P., Virtanen, K.A. (2015). Brown adipose tissue triglyceride content is associated with decreased insulin sensitivity, independently of age and obesity. Diabetes, Obesity and Metabolism. 17, 516–519.
  • U Din, M., Raiko, J., Saari, T., Saunavaara, V., Kudomi, N., Solin, O., Parkkola, R., Nuutila, P., Virtanen, K.A. (2017). Human brown fat radiodensity indicates underlying tissue composition and systemic metabolic health. The Journal of Clinical Endocrinology and Metabolism. 102, 2258–2267.
  • Koskensalo, K., Raiko, J., Saari, T., Saunavaara, V., Eskola, O., Nuutila, P., Saunavaara, J., Parkkola, R., Virtanen, K.A. (2017). Human brown adipose tissue temperature and fat fraction are related to its metabolic activity. The Journal of Clinical Endocrinology and Metabolism. 102, 1200–1207.
  • Holstila, M., Pesola, M., Saari, T., Koskensalo, K., Raiko, J., Borra, R.J.H., Nuutila, P., Parkkola, R., Virtanen, K.A. (2017). MR signal-fat-fraction analysis and T2* weighted imaging measure BAT reliably on humans without cold exposure. Metabolism. 70, 23–30.
  • Saari, T.J., Raiko, J., U-Din, M., Niemi, T., Taittonen, M., Laine, J., Savisto, N., Haaparanta- Solin, M., Nuutila, P., Virtanen, K.A. (2020). Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity. Scientific Reports. 10, 14373.

Latest Publications

Latest updates on the scientific publications of our group can be found via Google Scholar or ResearchGate

Doctoral Theses